Buy Orlistat Weight Loss Capsules Online

Start your weight loss journey with Orlistat 120mg capsules, available to buy conveniently online at Happy Pharmacy. Designed to support adults aiming to lose weight, Orlistat works best when combined with a healthy, low-fat diet and regular exercise. Our simple online consultation ensures you can access this treatment safely, with fast and discreet delivery straight to your door.

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What is Orlistat?

Orlistat 120mg capsules are a prescription medication used to support weight loss in adults. It is suitable for adults with a BMI of 30 or above, or 28 and above if you have weight-related health conditions such as type 2 diabetes, high blood pressure, or high cholesterol. Taken as part of a structured plan with a healthy diet and regular exercise, Orlistat can help you reach your weight loss goals safely. Always consult a healthcare professional before starting treatment to make sure it’s right for you.

Clinically Proven: Backed by extensive research.


Effective Weight-Loss Aid: Helps you lose more weight than dieting alone.


Prescription Medication: Safe and effective when used as directed by a healthcare professional.

How does Orlistat work?

Orlistat is a clinically proven, effective weight loss medication designed to support people who are overweight or obese by targeting the fat in your diet. Rather than suppressing appetite like some alternatives, orlistat prevents up to a third of dietary fat from being absorbed by your body. This approach helps reduce your overall calorie intake without directly affecting how hungry you feel.

Pharmacists often prescribe orlistat (also known by the brand names Xenical and Alli ) for patients who have struggled to lose weight through diet and exercise alone. The recommended dose of orlistat is typically taken three times a day with main meals that contain fat. For best results, it’s important to follow a balanced diet and stay active whilst taking orlistat.

Used correctly, orlistat is a weight management option that can help with steady, sustainable progress. While individual results vary, clinical research shows that people using it alongside healthy lifestyle changes lose significantly more weight than those relying on diet alone.

As with any medication, it’s important to be aware of the potential side effects of orlistat, especially if you consume a high amount of fat. To reduce discomfort, patients are advised to limit fatty meals and maintain a consistent eating pattern.

Clinically proven results

Clinical trials have shown that people taking Orlistat 120mg capsules can safely lose up to 10% more weight than with dieting alone making it a powerful option for those seeking long-term results.

Who can use Orlistat weight loss capsules

Orlistat weight loss capsules are suitable for adults who:

  • Have a BMI of 30 or higher (obesity), or
  • Have a BMI of 28 or higher with weight-related conditions such as type 2 diabetes, high blood pressure, high cholesterol or obstructive sleep apnoea.

Important: Orlistat is not suitable for pregnant or breastfeeding women or individuals with certain medical conditions, such as chronic malabsorption syndrome or cholestasis. Consult your GP or our pharmacists for advice.

When to take Orlistat weight loss capsules

  • Take one Orlistat 120mg capsule up to three times a day, just before, during, or within one hour after a main meal that contains fat.
  • If you skip a meal or if your meal contains no fat, you do not need to take Orlistat for that meal.

How to take Orlistat weight loss capsules

  • Swallow the capsule whole with water.
  • Do not take more than three capsules in 24 hours.

Dietary Guidance:

  • Stick to a reduced-calorie, low-fat diet while using Orlistat. Aim to have no more than 30% of your total daily calories coming from fat.
  • Spread your fat intake evenly across your three main meals to reduce the likelihood of side effects.

Side effects of Orlistat weight loss capsules

Like all medicines, Orlistat 120mg weight loss capsules can cause side effects, although not everybody gets them. Serious side effects are rare. These include: 

  • Severe allergic reaction. The signs of a severe allergic reaction include: severe breathing difficulties, sweating, rash, itching, swollen face, rapid heart beat, collapse.  Stop taking the capsules. Get medical help immediately.  
  • Bleeding from the back passage (rectum).
  • Diverticulitis (inflammation of the large intestine). Symptoms may include lower stomach (abdominal) pain, particularly on the left side, possibly with fever and constipation. 
  • Pancreatitis (inflammation of the pancreas). Symptoms may include severe abdominal pain sometimes radiating towards the back, possibly with fever, nausea and vomiting.  
  • Skin blistering (including blisters that burst).
  • Severe stomach pain caused by gallstones.
  • Hepatitis (inflammation of the liver). Symptoms can include yellowing skin and eyes, itching, dark coloured urine, stomach pain and liver tenderness (indicated by pain under the front of the rib cage on your right hand side), sometimes with loss of appetite.  
  • Oxalate nephropathy (build up of calcium oxalate which may lead to kidney stones).  

Read the Orlistat 120mg patient information leaflet for more information on possible side effects.

Stop taking the capsules and tell your doctor if you notice any of these side effects.

Always follow the directions for use and consult your GP or pharmacist if you experience unusual symptoms. 

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Additional Information

Benefits of Orlistat

1. Clinically Proven Weight Loss

Orlistat helps you lose more weight than dieting alone, with studies showing significant reductions in body weight when used alongside a healthy diet and exercise.

2. Long-Term Weight Management

Orlistat not only helps you lose weight but also supports maintaining a healthier weight by encouraging sustainable lifestyle changes.

3. Reduces Risk of Weight-Related Conditions

Weight loss with Orlistat can help reduce the risk of conditions like type 2 diabetes, high blood pressure, and heart disease.

4. Simple, Targeted Action

Unlike appetite suppressants, Orlistat works directly in your digestive system, making it a focused and effective solution for weight loss.

FAQs

What is Orlistat used for?

Orlistat is used to help adults who are overweight or obese lose weight. It works by blocking the absorption of dietary fat in the digestive system.

Do I need a prescription for Orlistat?

Yes, Orlistat 120mg is a prescription-only medication. The supply of Orlistat is only made if it is safe and appropriate, following assessment by one of our clinical team.

How much weight can I expect to lose with Orlistat?

Studies show that Orlistat can help you lose up to 10% more weight than dieting alone, provided you follow a reduced-calorie, low-fat diet.

Can I eat normally while taking Orlistat?

To minimise side effects, it’s important to follow a low-fat diet while taking Orlistat.

Meals should ideally contain no more than 30% of their calories from fat.

Orlistat reduces the absorption of supplements of some fat soluble nutrients, particularly betacarotene and vitamin E.

You should therefore follow your doctor’s advice in taking a well balanced diet rich in fruit and vegetables.

Your doctor or pharmacist may suggest you take a multivitamin supplement.

Orlistat Side Effects

Side Effects and Safety Information

Orlistat is generally well-tolerated, but some common side effects include:

  • Oily spotting or stools.
  • Increased frequency of bowel movements.
  • Flatulence with discharge.

These effects are related to the way Orlistat works and can often be managed by sticking to a low-fat diet. Always read the patient information leaflet for a full list of potential side effects and consult your GP or pharmacist for further information if needed.

Support

Whether you have questions about your Alli treatment, need tips for managing side effects, or require advice on dosing, our Happy Pharmacy healthcare team is here for you.
Your health is our priority— contact us any time

Medically Reviewed & Written by our GPhC registered Pharmacists

Palvinder Deol, GPhC Number 2047066

GPhC-registered Superintendent Pharmacist with over 25 years of experience in pharmaceutical care. Pavel Graduated from as a qualified pharmacist from the University of Bath in 1997.

Nigel Howard - independent Prescriber

Nigel Howard, GPhc Number 2047450

GPhC-registered Independent Prescriber with extensive experience in primary care and clinical pharmacy. Nigel qualified as a pharmacist in 1997 and has since specialised in prescribing for a wide range of health conditions.

Last reviewed: 10th September 2025