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Erectile dysfunction (ED) affects approximately 4.3 million men in the UK, with prevalence increasing with age. Beyond the physical symptoms, ED can significantly impact relationships, self-esteem, and overall quality of life. Fortunately, effective treatments like sildenafil have revolutionised the management of this common condition.


Understanding Erectile Dysfunction

Erectile dysfunction occurs when a man consistently struggles to achieve or maintain an erection firm enough for sexual activity. While occasional difficulties are normal, persistent problems warrant attention.

ED often results from reduced blood flow to the penis, frequently caused by underlying vascular issues, diabetes, high blood pressure, or psychological factors. [1]

Many men delay seeking treatment due to embarrassment, potentially missing early signs of serious health conditions—as ED can be an early warning sign of cardiovascular disease or diabetes.


How Sildenafil Works

Sildenafil (commonly known by the brand name Viagra) belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. It works by enhancing the effects of nitric oxide, a natural chemical the body produces that relaxes muscles in the penis and increases blood flow.

When sexual stimulation occurs, nitric oxide is released in the erectile tissue, activating an enzyme that produces cyclic guanosine monophosphate (cGMP). Sildenafil prevents the breakdown of cGMP, allowing it to accumulate and prolong the erection process.


Effectiveness and Expectations

Clinical studies show that sildenafil effectively helps approximately 70% of men with ED achieve improved erections. [2] The medication typically begins working within 30-60 minutes, and its effects can last for up to 4 hours, though this varies between individuals.

It's important to understand that sildenafil doesn't cause spontaneous erections—sexual stimulation is still required. The medication simply facilitates the natural process when arousal occurs.


Accessing Sildenafil Through Happy Pharmacy

At Happy Pharmacy, we offer confidential erectile dysfunction consultations where our healthcare practitioners can assess your suitability for sildenafil treatment. During these consultations, we'll discuss your medical history, current medications, and lifestyle factors to determine whether sildenafil is appropriate for you.

For suitable candidates, we can prescribe sildenafil as part of a comprehensive approach to managing erectile dysfunction, taking into account both physical and psychological aspects of sexual health. 



Take the Next Step

Complete an erectile dysfunction consultation today to discuss whether sildenafil from Happy Pharmacy could help improve your sexual wellbeing.


 

Blog medically reviewed by : Palvinder Deol, GPhC Registered Pharmacist, 19 May 2025

 


References:

  1. Yafi FA, Jenkins L, Albersen M, et al. Erectile dysfunction. Nat Rev Dis Primers. 2016;2:16003.

  2. Goldstein I, Lue TF, Padma-Nathan H, et al. Oral sildenafil in the treatment of erectile dysfunction. N Engl J Med. 1998;338(20):1397-1404.

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